Norwich started life in Coca-Cola League One in the worst possible fashion as they were hammered 7-1 at home by Colchester.
Kevin Lisbie's opener, a double from Clive Platt and a goal from David Fox meant the visitors were in firm control by the 22nd minute, and Lisbie added another before the break.
Cody McDonald grabbed one back for Norwich, who were relegated from the Championship in May, but further goals from David Perkins and Scott Vernon completed the hosts' humiliation.
Striker Jermaine Beckford's double gave Leeds a 2-1 win over 10-man Exeter at Elland Road.
Beckford scored his first in the 13th minute and events went from bad to worse for the visitors when Barry Corr was sent off on his debut on the hour mark.
Alex Russell equalised for the newly-promoted side but Beckford spared Leeds' blushes two minutes from time.
Southampton, with a new manager and new owners and having started the season on minus 10 points, began life in the third tier for the first time since 1960 with a 1-1 draw at Millwall.
Matthew Paterson gave them the lead with a tidy finish and it seemed as if their luck had changed when Kelvin Davis saved Alan Dunne's penalty, but Southampton's reprieve was short-lived as Nadjim Abdou headed Millwall's equaliser in the 67th minute.
Goals from Christian Dailly, Nick Bailey and Miguel Angel Llera ensured Charlton edged a five-goal thriller against Wycombe at The Valley.
The Addicks raced into a two-goal lead inside 23 minutes through Dailly and Bailey, before Wycombe's Chris Zebroski scored the first of his double. Llera's debut strike in the 50th minute was to prove the winner.
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