Leaders West Brom ran amok at second-placed Middlesbrough to claim a 5-0 victory in the Coca-Cola Championship's match of the day.
Northern Ireland midfielder Chris Brunt fired the first of his two goals into the bottom corner from just outside the penalty area in the 17th minute and sent a 35-yard rocket high into the centre of goal just after the half-hour mark before Youssouf Mulumbu headed home Graham Dorrans' left-wing cross.
Roman Bednar and Jerome Thomas added to the score in the final 10 minutes to pile the misery on Middlesbrough, who slipped to their first home league defeat of the season.
Newcastle replace their north-east neighbours in second place following a 3-1 victory against winless Plymouth, with Steven Taylor, Kevin Nolan and Andrew Carroll on target.
Jay Simpson swept QPR ahead in the 19th minute at promotion hopefuls Cardiff and doubled his personal tally five minutes before the interval to give the visitors a 2-0 win.
Lee Martin's first goal for Ipswich eased the pressure on manager Roy Keane but it was still not enough to give them their first win of the season in a thrilling 3-3 draw at Doncaster.
Blackpool's highly-rated midfielder Charlie Adam's 19th-minute strike was enough to send Ian Holloway's side to victory at Nottingham Forest, who fell to their third league defeat on home soil this season.
George Boyd's stoppage-time strike gave Peterborough their first victory of the season, with a 3-2 win at home to Reading.
Watford almost also came back from two goals down to take all three points but Dany N'Guessan headed home a stoppage-time equaliser for Leicester to draw 3-3.
Elsewhere, Preston came from behind to beat Coventry 3-2, Grant McCann's stoppage-time goal gave Scunthorpe a 1-1 draw at Bristol City. Barnsley against Swansea ended goaless, while Darren Ambrose's 55th-minute strike gave Crystal Palace a 1-0 win at home to Derby.
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