Southampton will meet Charlton at St Mary's in the quarter-finals of the Johnstone's Paint Trophy.
The clash, which would have been a Premier League encounter just five seasons ago, is the pick of the draw in a Southern section which also includes a derby clash between MK Dons and Northampton at Stadium:mk.
The Southern draw also sees Hereford travel to Leyton Orient and Swindon face Norwich at the County Ground.
In the Northern section, League One leaders Leeds face Grimsby, Accrington or Shrewsbury take on Bury, Bradford host Port Vale and Carlisle travel to Chesterfield.
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