Huddersfield's Tom Clarke will be missing from the squad to face Tranmere at the Galpharm Stadium after undergoing knee surgery.
Clarke, who can play in either midfield or defence, will be sidelined for up to six weeks after having an exploratory operation on the same knee that kept him sidelined for three months earlier this season.
Clarke, brother of central defender Nathan, missed the weekend's FA Cup win at Port Vale, as did winger Anthony Pilkington, who was rested due to a thigh strain.
Pilkington is expected to return against Tranmere, but Terriers manager Lee Clark will still be without striker Robbie Simpson and Danny Drinkwater, on loan from Manchester United, as both players are struggling with thigh injuries.
Clark has no other new injury or suspension problems as Town look to bounce back from the 2-1 defeat at Swindon in their last league outing.
Tranmere will be without Chris Shuker as they look to record back-to-back league wins for the first time this season.
Shuker limped out of Saturday's goalless FA Cup draw against Aldershot with an ankle injury and is likely to be replaced by Ian Thomas-Moore.
Rovers caretaker boss Les Parry has no other fresh injury worries and is not expected to make any further changes to his side.
Long-term absentees Alan Mahon and Bas Savage do remain on the sidelines, however, with their respective ankle and Achilles problems.
Tranmere are rooted to the foot of League One but did manage a morale-boosting 2-0 victory over Southend in their last league outing and will be determined to build on that success.
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