Tranmere caretaker boss Les Parry is hoping winger Chris Shuker will be passed fit for the home clash with Brentford.
Shuker has been struggling with an ankle injury but is edging closer to a full recovery and is described by Parry as "touch and go".
Forward Ian Thomas-Moore sustained a foot injury in Tuesday's 3-3 draw at Huddersfield and is rated as a major doubt.
On-loan Manchester City defender Shaleum Logan is nursing an abductor problem but could again be asked to play through the pain barrier.
Rovers battled back three times to claim a point at Huddersfield and have collected four points from their last two outings.
Parry declared: "Nobody expected us to get anything on Tuesday and the point was fantastic. The other thing we get from it is the confidence boost."
Brentford boss Andy Scott is set to name an unchanged line-up.
Winger Myles Weston will travel with the squad after his recent hamstring injury but, with the Bees going into the match on the back of successive 1-0 wins, he is unlikely to be risked.
Goalkeeper Nikki Bull is the only other injury absentee following a shoulder operation.
Arsenal loanee Wojciech Szczesny will therefore keep his place in goal with youngster Simon Moore providing cover on the bench and Derby keeper Lewis Price missing out again due to the five-loanee rule.
Tottenham teenager John Bostock will start on the right wing having this week revealed he would be happy to extend his loan spell with the west Londoners.
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