Darlington manager Steve Staunton is expected to hand new signing Simon Madden his full debut in the home clash with Northampton.
Madden, one of six new signings made by manager Steve Staunton since the turn of the year, was suspended for recent win at Rotherham and was a half-time substitute in Saturday's defeat at Crewe.
Staunton, who has no new injury or suspension problems, is not expected to make too many changes after fielding the same side that had secured their first away win at Rotherham last week against Crewe.
All six of Staunton's recent signings - Gary Dempsey, Gary Waite, Tadgh Purcell, Alan White and Patrick Deane - either started or were on the bench at Gresty Road. Dan Groves (foot) and Mark Bower (ankle) remain sidelined.
Northampton goalkeeper Chris Dunn could move to within 10 minutes of a new club record.
Dunn, 22, last conceded a goal against Port Vale on December 12 and is closing in on Alan Starling's record of 595 minutes without picking the ball out the net for the Cobblers.
Sampson saw his side fail to take their chances in a goalless draw at home to Chesterfield on Saturday and may rotate his strike force, with Courtney Herbert and Stephen O'Flynn pushing for a start.
Striker Steve Guinan (hernia) and winger Liam Davis (foot) remain the only absentees as Sampson looks to extend the Cobblers' unbeaten run to eight games.
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: http://gms.to/writeforgms