Manchester City's Ivory Coast defender Kolo Toure will be available against Portsmouth after returning from the African Nations Cup.
Former Arsenal midfielder Patrick Vieira remains sidelined with a calf injury but could face Hull a week on Saturday.
Benjani Mwaruwari is unlikely to feature as the striker has been linked with a move to Sunderland, while Robinho has joined Santos on loan.
Ahead of the game, Roberto Mancini says is intent on maintaining Manchester City's tradition of giving bright young players a chance.
Dedryck Boyata, Abdi Ibrahim and Greg Cunningham are the latest batch to come off the production line. They are following in the footsteps of Micah Richards, Stephen Ireland, Nedum Onuoha and Michael Johnson, who have come through the ranks.
Boyata played in both Carling Cup semi-final matches against Manchester United after catching Mancini's eye. Even though Wayne Rooney secured a dramatic stoppage-time winner for the holders, Boyata had reason to be satisfied with his displays.
Mancini said: "Boyata played against Rooney and Ryan Giggs and did well in both games.
"I am happy for these young players - they are very talented. I hope they continue to train well and improve.
"They have a chance but it is important they keep their feet on the ground and work hard."
Portsmouth manager Avram Grant is set to welcome midfielder Jamie O'Hara back into his side for the trip.
O'Hara has returned to Fratton Park on loan from Tottenham until the end of the season but defender Younes Kaboul and goalkeeper Asmir Begovic are on the verge of completing transfers in the opposite direction.
Pompey are still waiting for Kanu, Nadir Belhadj and Hassan Yebda to return from the African Nations Cup while Lens loanee Aruna Dindane is set to join Birmingham.
Tommy Smith (groin) and Papa Bouba Diop (hamstring) are doubts for the Eastlands game while David Nugent is back after his loan spell at Burnley ended.
Returning midfielder O'Hara has not given up hope of keeping the club in the Barclays Premier League.
O'Hara's comeback is a welcome ray of light for manager Grant, who is expected to lose defender Kaboul and goalkeeper Begovic. There are also doubts over whether Ivorian international Dindane will return to Fratton Park, after parent club Lens tried to sell him to Birmingham.
Despite this, O'Hara is certain Pompey still have what it takes to close the five-point gap between them and Premier League safety.
He told the club's official website: "I still think we can do it (stay up), otherwise I wouldn't have come back.
"It might take me a couple of games to get back to full match fitness because I haven't been playing at Spurs. But I've only missed two Premier League games for Pompey and I'm hoping to carry on where I left off."
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