Tottenham forward Eidur Gudjohnsen is in the squad for the Barclays Premier League clash against Aston Villa at White Hart Lane after his arrival just before the transfer deadline.
Younes Kaboul, another January signing, is available after being ineligible for the FA Cup win over Leeds in midweek, with Kyle Walker in contention after returning from a loan spell at Sheffield United.
Roman Pavlyuchenko, Benoit Assou-Ekotto, Aaron Lennon, Jonathan Woodgate (all groin) are out, while Carlo Cudicini (wrists and pelvis) is a long-term absentee. Ledley King will need a late test on his knee.
Striker Jermain Defoe feels Tottenham are playing well enough to beat Aston Villa or anyone else as they continue their quest for a Champions League spot.
Both Spurs and Villa are battling for fourth in the Barclays Premier League and the game at White Hart Lane could prove vital in the final shake-up.
"That's a big game for us, a massive game," said Defoe, whose side currently occupy fourth. "Villa are a good side, they've got a great manager and they're playing well.
"But the way we're playing we're confident going into every game."
Aston Villa are set to be boosted by the return of striker John Carew.
The Norway international, who has missed the last four games with a knee injury, has been back in training this week and manager Martin O'Neill hopes to have him available at White Hart Lane.
Stephen Warnock is continuing to struggle with the shin injury he picked up during the FA Cup victory against Brighton last month.
He is facing a race against time to be fit for the Carling Cup final against Manchester United at Wembley on February 28.
Captain Stiliyan Petrov retains his place in the side despite still being troubled by an Achilles problem.
Villa manager Martin O'Neill has warned his players that they cannot afford to slip up against Tottenham.
O'Neill said: "The Tottenham game is a big, big game for us.
"Tottenham have been going great. They have some real quality players and have got strength in depth, which perhaps they may have lacked a couple of years ago.
"It augurs well for them as they played very well in the FA Cup replay up at Leeds and they will be ready for our match. They are a very fine side as they proved here at Villa Park not so long ago.
"It is up to us but I think we are a fine side ourselves. The results we have had recently may not completely have reflected the manner in which we have played.
"I'm thinking in particular about the games we had against Liverpool and West Ham when we might easily have had four points and finished with one.
"We were back on track again against Fulham. That was a difficult game for us to negotiate and it is up to us do the same on Saturday against Tottenham."
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