Wigan defender Titus Bramble is a major doubt for the visit of Tottenham to the DW Stadium on Sunday.
The centre-back sustained a hamstring injury in Wednesday's goalless draw at home to Bolton and is unlikely to be fit in time.
Should that be the case Emmerson Boyce will probably replace Bramble in the starting line-up, although manager Roberto Martinez has the option of dropping midfielder Paul Scharner back into defence.
Martinez feels he has a much stronger squad than when they first met Spurs this
season and is confident they will be successful in their survival battle.
"Looking back I am proud of the way we have matured and really found out a lot about people at the club," he said of the way the players had responded to that potentially-damaging 9-1 defeat.
"I felt we have improved a lot on what we have shown in the first half of the campaign.
"We look like a team that has a real pride in what we are doing and the next little bit is to find a bit more composure in the final third.
"Now I feel the squad is at its strongest and I'm really excited going into the last third of the season."
Spurs have had a difficult run since the turn of the year, winning just one of six league matches and scoring just once.
However, Martinez insists tomorrow is not an occasion for revenge.
"It is important we don't play the occasion of facing Spurs in the league," he stressed.
"Now it is a completely different game but when you play such a talented side like Spurs there is never a good or bad time to play them.
"If they are on a bad run you expect them to change it, if they are on a good run they will be playing with confidence.
"When you play good sides you need to focus on yourself and unless we are at our best we will not be able to compete with them."
Tottenham winger Aaron Lennon has still not recovered from a groin injury and will miss the Barclays Premier League trip to Wigan.
Ledley King (knee) will require a late check, as will Jermaine Jenas (groin) but Younes Kaboul and Kyle Walker are available again after being cup-tied last week.
Jonathan Woodgate (groin), Benoit Assou-Ekotto and Carlo Cudicini (wrist and pelvis) are out.
Spurs have seen the goals dry up recently and have fallen out of the top four of the Premier League but boss Harry Redknapp is still happy with progress after being appointed 16 months ago when they were bottom of the table.
Redknapp points out his team are still in the FA Cup and can still qualify for the Champions League if they find their goalscoring touch again, starting with the trip to Wigan this weekend.
"Listen, if you'd said at the start of the year we'd be where we are, and still in the FA Cup, I think everyone would have said 'fantastic'," Redknapp said.
"People get carried away. Suddenly people think we're going to get in the Champions league. We can still make the Champions League, make no mistakes.
"We've still got a great chance of making the Champions League and I'm delighted with how we've done, fantastic. We've played some great football.
"I still want to get into the Champions League and I think we've got as good a chance as any. I don't see any reason we can't do it, we've got a big chance. It's going to be an exciting end to the season."
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