Chelsea were beaten 1-0 by relegation threatened West Ham United on Saturday lunchtime to end any lingering hopes of a title challenge.
Marko Arnautovic scored the winner in the sixth minute to help David Moyes to his first win since taking charge.
Five of Antonio Conte's nine Premier League defeats as Chelsea manager have come in London derbies.
The Blues were close to full strength but failed to register a single shot on target in the second half of their disappointing defeat.
Key midfielder N'Golo Kante joined Chelsea for £30m in 2016 and he was unquestionably the standout player in last season's title win.
However, he could do little to help Conte's side against West Ham.
Kante's horrendous moment
The former Leicester City man is widely considered one of the finest midfielders in the Premier League - but he was not at his best on Saturday.
Early in the second half, Kante produced a moment which perfectly summed up Chelsea's performance at the Olympic Stadium.
Evoking memories of Renato Sanches' humiliating moment for Swansea in November, Kante calmly stroked the ball out of play with a horrendous misplaced pass.
Speaking ahead of the shock defeat at West Ham, Antonio Conte claimed he would back Kante to win the Ballon d'Or.
“When I was a player I wanted to win the Ballon d’Or but I knew my characteristics, I knew that it was impossible,” Conte said.
“But I won a lot in my career. I won everything. I don’t know if Kanté can win the Ballon d’Or in his life because of the characteristics of this player. He doesn’t score a lot of goals. He is a great worker.
“For me as a coach Kanté has to win, but in reality it would be very difficult. Paolo Maldini never won but he was the best defender in the world. Gianluigi Buffon never won, he was the best goalkeeper in the world for many years. But this is the story of the Ballon d’Or."
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