Leyton Orient skipper Stephen Purches and striker Scott McGleish need fitness tests ahead of the home meeting with Hartlepool.
Defender Purches, who is trying to shake off the torn calf which has kept him out of the last two matches, was able to begin light training earlier this week.
Veteran frontman McGleish missed last weekend's defeat at Brentford with a foot injury, and both players are rated 50/50 to be fit.
Aston Villa loanee Eric Lichaj made his debut at Griffin Park and will keep his place at right-back if Purches is ruled out. The American, who put in an impressive display, can also play at left-back so Charlie Daniels' place may be under threat.
James Scowcroft was drafted into the starting line-up in place of McGleish.
Winger Aaron Doran has returned to Blackburn at the end of his loan spell.
Hartlepool will monitor Gary Liddle and Andy Monkhouse.
Central defender Liddle has missed the last three games with a hip problem, but could be back in contention if he proves his fitness ahead of the game at Brisbane Road.
Monkhouse sustained a gashed knee during last weekend's 1-0 defeat by Swindon after colliding with a photographer, but he will be hoping to recover in time to feature.
James Brown came off the bench to replace Monkhouse on Saturday and staked a claim for a starting berth by scoring the only goal of the game as the Pools' reserves claimed a 1-0 win over Huddersfield.
Peter Hartley also featured for the second string after having been rested at the weekend and will be hoping to return to the senior side against the Os.
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