Swansea could welcome Albert Serran back into their squad for Monday`s clash with Scunthorpe.
The defender, who has been plagued with injuries throughout the season, has trained all week and could make his first appearance since January.
David Cotterill, Shefki Kuqi and Mark Gower all came off the bench in Saturday's south Wales derby defeat to Cardiff and will be hoping to figure from the start this time around.
Lee Trundle, who was an unused substitute at the weekend, may also be handed a starting role.
Fede Bessone (knee), Ferrie Bodde (calf) and Jordi Lopez (ankle) remain on the sidelines.
Sousa will be expecting a response to the dramatic loss at the Cardiff City Stadium as his side look to cement a play-off place.
Scunthorpe manager Nigel Adkins welcomes back captain Cliff Byrne.
The 27-year-old defender is set to return at the Liberty Stadium after completing a five-match ban following his third red card of the season against Ipswich last month.
Kenny Milne will miss out after starting only his second game in 19 months against Blackpool on Friday.
Niall Canavan could come in for Rob Jones, who has been struggling with a knee problem in recent weeks, while Adkins will hand a late fitness test to David Mirfin (calf).
Ian Morris is ruled out with a knee injury and may be joined on the sidelines by midfielder Sam Togwell and left-back Marcus Williams, who are both doubts after picking up knocks on Friday.
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