Darlington striker Tadgh Purcell is rated "touch and go" for the visit of relegation-threatened Grimsby.
The Irishman netted his ninth goal of the season before sustaining an ankle problem in the first half of Tuesday's 3-3 draw at Cheltenham.
Purcell has been unable to take part in training since, so will be assessed again before Simon Davey names his side.
Josh Gray and Mor Diop (both ankle) are doubtful, while Ian Miller (hernia) may again miss out.
Paul Arnison continues to struggle with a hamstring injury so Mark Bower should retain his place in the Quakers' defence.
Curtis Main continues to struggle with ankle ligament damage, while Gareth Waite will also be missing for the remaining four games of the season after undergoing surgery this week.
On-loan midfielder Dean Sinclair will be a major loss for Grimsby.
Sinclair, who is on loan from Charlton, was forced off just 25 minutes into the morale-sapping 3-0 home defeat to Torquay last weekend with a hamstring problem.
He has returned to The Valley for treatment and the injury could mean a premature end to his season with three matches remaining.
Peter Sweeney, Sinclair`s replacement against Torquay, is likely to return to the starting line-up, while Lee Peacock, Adrian Forbes, Michael Leary, Paul Linwood, Nick Hegarty, Adam Proudlock and Jude Stirling are available should manager Neil Woods wish to make any further changes.
Defeat would see Grimsby follow Darlington out of the Football League. A draw will also send Town down if Barnet get a point at home to Rotherham.
If Barnet win, Lincoln beat Bury and Cheltenham get at least a point at home to Aldershot, Grimsby will be relegated regardless of the result at the Darlington Arena.
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