Peter Crouch will miss the Euro 2012 qualifiers against Bulgaria and Switzerland due to a back injury.
The Tottenham striker was always going to be a major doubt once club boss Harry Redknapp revealed what he thought was a rib problem after Saturday's surprise home defeat to Wigan.
Coach Fabio Capello took the precaution of naming an additional striker in his 24-man squad, so when it was confirmed on Wednesday afternoon Crouch had returned to Spurs for treatment, there was no requirement for a replacement to be drafted in.
As Bobby Zamora was ruled out prior to the squad being announced, it leaves Capello to choose from Wayne Rooney, Carlton Cole, Darren Bent and Jermain Defoe, who has recovered from a groin complaint, amongst his striking options.
The Football Association opted not to make any further injury announcements, although the fact Crouch is the only player being released and no call-ups have been requested must be viewed as good news given England only had one goalkeeper at training on Tuesday.
There is cover for Phil Jagielka, who also sat out training on Tuesday with an ankle problem which David Moyes revealed made him an extreme doubt following Everton's defeat at Aston Villa on Sunday.
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