Liverpool blew one of their best chances of winning a trophy this season after suffering an embarrassing 4-2 penalty shoot-out Carling Cup defeat against League Two side Northampton at Anfield.
Having taken a ninth-minute lead through Milan Jovanovic, his first goal since joining the club from Standard Liege in the summer, the hosts should have wrapped up the third round tie.
But Billy McKay and Michael Jacobs turned things around and although David Ngog snatched a late equaliser the Cobblers went through on spot-kicks with Abdul Osman scoring the decisive penalty.
West Brom roared back from a half-time deficit to send Manchester City tumbling out with a 2-1 victory at The Hawthorns.
Gianni Zuiverloon and Simon Cox turned the match on its head, scoring within two minutes of each other after Jo had put City in front midway through the first half.
It was a dismal result for Blues boss Roberto Mancini, who was forced to field an inexperienced side due to a combination of injury and Saturday's Premier League match with Chelsea, but saw the first chance of silverware disappear at the earliest opportunity.
Wigan staged a dramatic late fightback to snatch a place in the fourth round with a 2-1 victory over valiant Preston.
Jordi Gomez and Charles N'Zogbia struck in the closing three minutes as the Premier League side prevailed at the DW Stadium.
Preston had led after Keith Treacy opened the scoring in the 23rd minute and hit the woodwork twice through Paul Coutts.
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