Colchester will check on defenders Pat Baldwin and Brian Wilson ahead of the home game against Dagenham.
Centre-half Baldwin missed Saturday's 3-1 win over Tranmere with the ankle injury he suffered at Southampton seven days earlier, while right-back Wilson has sat out the last two games with an ankle problem.
Paul Reid and John White are currently deputising in the back four.
Striker Steven Gillespie was an unused substitute at the weekend after a long battle for fitness following an ankle injury and should be involved again.
Midfielder John-Joe O'Toole and defender Morten Knudsen (both knee) remain long-term absentees.
The Us are still unbeaten in the league and moved up to fifth following Saturday's victory.
Dagenham defender Phil Ifil will keep his place against a former side.
The former Spurs right-back is enjoying an extended run in the starting XI as first choice Abu Ogogo continues to recover from a hamstring injury.
Ogogo is joined on the sidelines by fellow defender Will Antwi who also has a hamstring injury - though both could be back in contention by the weekend.
Former Reading, Brighton and Tranmere striker Bas Savage is still not match fit after an operation during the summer but will keep his place after impressing during the 2-2 draw at Charlton at the weekend.
Colchester captain Magnus Okuonghae will come up against his former side after leaving in summer 2009 having won the player of the year award for the Daggers.
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: http://gms.to/writeforgms