Pablo Zabaleta will miss Manchester City's Premier League clash with Newcastle.
The Argentina-born utility man suffered a hamstring strain against Juventus on Thursday night, which will either mean a recall for Dedryck Boyata or Joleon Lescott.
David Silva, James Milner and Nigel de Jong will all hope for a place in the starting XI after starting the Juventus draw on the bench following their roles in last weekend's win over Chelsea.
Adam Johnson is anxious to start against his boyhood idols.
Johnson, a £7million signing from Middlesbrough in January, scored in the 1-1 draw against Juventus in the Europa League in midweek and is eyeing more game time as the focus switches back to the Barclays Premier League.
He said: "I was at Newcastle when I was a kid from 10-12 before I went to Middlesbrough.
"So I grew up supporting Newcastle and David Ginola and players like that. It's fantastic to playing against north-east teams.
"These are the type of games I want to be playing in."
Johnson's team-mate Jerome Boateng is ready to make his first start in the Premier League after a knee problem.
Boateng, 21, who arrived from Hamburg over the summer, proved his fitness in the draw with Juventus and is keen to feature against the Magpies.
He said: "I would like to play on Sunday. It is going to be a hard game. I am happy I am now 100% and can play.
"It is important I get some games and help the team after coming to a new club and getting injured."
City go into the match in buoyant mood after beating champions Chelsea last weekend.
But Boateng believes they need to start beating teams with a lower profile if they are to be taken seriously.
He added: "We can have success if we play like we did against Chelsea. You do not have to tell the players about Chelsea.
"But if you want to be the best you have to beat other smaller teams. I hope I play a lot and we have success. Title challengers? I think so."
Newcastle defender Sol Campbell has shaken off a thigh injury.
The 36-year-old missed last weekend's 2-1 home defeat by Stoke after suffering a slight thigh problem on his senior debut for the club at Chelsea, but is back in contention for the game at Eastlands.
Danny Guthrie (knee) and Danny Simpson (ankle) are both back in full training and will play for the reserves next week, while Steven Taylor (shoulder) is expected to resume training in a fortnight's time, leaving only Steve Harper (shoulder) and Dan Gosling (knee) on the long-term casualty list.
Hughton watched City draw 1-1 with Juventus in the Europa League on Thursday evening, and knows opposite number Roberto Mancini has enviable options for the encounter.
He said: "They are a team full of quality. You look at the bench they had and perhaps even more so, look at the players who didn't even make the bench."
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: http://gms.to/writeforgms