Steve Tilson takes charge of Lincoln for the first time when Stockport visit Sincil Bank.
The former Southend boss officially succeeded Chris Sutton as manager on Monday, despite agreeing to take the job last weekend and attending the Imps` defeat at Shrewsbury.
Tilson could have Drewe Broughton available after the big striker played an hour for the reserves following a leg injury.
However, teenager Kern Miller limped out of that reserve game with a hamstring injury leaving Tilson with only two fit centre-backs.
Delroy Facey is still away on international duty with Grenada, while fellow forward Andy Hutchinson (broken foot) and defender Paul Green (thigh) also remain out.
Stockport boss Paul Simpson will check on the fitness of several players.
A number of Simpson's squad are nursing minor niggles but the County boss has no major concerns as his side seek to build on last weekend's home win over Barnet.
Stockport picked up their first home victory since February after they battled back from a goal down to beat the Bees 2-1.
Simpson handed a debut to on-loan Burnley striker Wes Fletcher and he looks set to continue up front alongside George Donnelly.
Simpson said: "I thought George and Wes showed a good understanding up front. The two of them worked extremely hard and we've got to make sure we build on that now."
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