Oxford manager Chris Wilder will make changes to his defence for the visit of Northampton.
Wilder witnessed his side throw away a 2-0 goal lead to lose 3-2 against Macclesfield last week and needs to tighten up his backline.
Jake Wright will definitely play at the Kassam Stadium after he returned to training this week following an injury and Mark Creighton may also feature in the U's defence.
Damien Batt has returned to training after a spell on the sidelines but it is not known whether Saturday's game against the Cobblers will come too soon for the defender.
Oxford need a response after two successive defeats and Wilder could promote Jack Midson and Mitchell Cole to the starting line-up after warming the bench in recent weeks.
Northampton will be without defender Ben Tozer for the trip.
Tozer was sent-off in the dying stages of last weekend`s humiliating 4-3 home defeat to Hereford and would have been due to begin a three-match ban.
However, his loan spell from Newcastle has ended so the player has returned to the north east. Fellow centre-half Dean Beckwith is out as he serves the second of a three-match ban of his own so manager Ian Sampson has problems in defence.
Right-backs Paul Rodgers and John Johnson could be considered to fill in alongside captain Andy Holt while Sampson is still hopeful of signing a new defender on loan in time for the game.
Craig Hinton will not be considered despite his return to training from a knee injury but the former Bristol Rovers defender could be on the bench.
Midfielder Abdul Osman (calf) is a doubt after he came off against Hereford while striker Leon McKenzie will be looking to build on his first-half hat-trick last weekend. Tadhg Purcell (knee) is out for the season.
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