Fulham hope midfielders Danny Murphy and Simon Davies will return for the Barclays Premier League clash with Wigan.
Murphy (abductor strain) and Davies (ankle) sat out last weekend's 2-1 defeat at West Brom.
Dickson Etuhu (ankle) and Damien Duff (calf) remain sidelined, but could return within the next two weeks.
Manager Mark Hughes is unconcerned by Fulham's slide down the table as they seek to avoid a third successive defeat against Wigan.
They lie in 16th place, level on points with Liverpool who sit in the relegation zone, and are in danger of squandering their promising start to the season.
"We struggled against West Brom last weekend because of the injuries but prior to that we were unbeaten until two games ago," Hughes said.
"We acquitted ourselves very well in the Tottenham game. I was unhappy with a couple of decisions that went against us.
"Overall I've been delighted with our performances, if you take the West Brom game out of it. We need to pick up three points tomorrow and our home form is good, so the expectation is we have a good chance.
"Four out of our next six games are at home and we anticipate we'll pick up points in those games. Irrespective of who the opposition is, we'll give them a good game at home.
"Away from home our form isn't great and we're trying to change that. What kind of season we have will depend on our form on the road."
Wigan defender Steven Gohouri could be available for the trip to London.
Gohouri has missed three games due to a calf problem but may be fit to return to action at Craven Cottage.
Latics boss Roberto Martinez will assess Gary Caldwell after the captain played 90 minutes against Swansea in the Carling Cup on Tuesday, his first Wigan appearance since undergoing double hip surgery over the summer.
Tom Cleverley comes back into the squad having been ineligible for that game, while Emmerson Boyce (hamstring) and James McCarthy (ankle ligament damage) remain sidelined.
Martinez has praised Hughes for the job he has done since stepping into Roy Hodgson's shoes at Fulham and expects to see the London outfit continue on an upward trend under the Welshman.
Hughes had a tough act to follow when he was appointed manager at Craven Cottage in July, taking over from Hodgson, who arrived in December 2007 and led the club from the brink of relegation to a record-high seventh place in the Barclays Premier League in the space of a season-and-a-half.
Fulham then reached the Europa League final in May this year before Hodgson's defection to Liverpool.
Hughes picked up the baton from there and has overseen one win, six draws and two defeats from nine league fixtures so far this term.
It has been a steady start, but Martinez thinks the Cottagers' prospects look good with Hughes at the helm.
"I think that was probably the hardest job to take in Fulham's history if you look at the achievements Roy Hodgson had domestically and in European competition," Martinez said.
"But they have changed the way they play slightly and they have bought one or two players who have given them a different dimension.
"You just feel that Fulham will take the success of the previous two or three seasons and will use that to take the team to a different level. That is full credit to Mark Hughes."
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