Rotherham will be missing skipper Ryan Cresswell when they host Northampton.
The centre-half missed Saturday's win at Crewe with a recurring back problem and he is not expected to be fit for the visit of the Cobblers.
Tom Newey will serve a one-match ban following his fifth caution of the season so Jamie Green will fill in at left-back.
Boss Ronnie Moore is hoping to have better news in the goalkeeping department with the potential return of number one Andy Warrington.
Warrington has missed the last two games following the birth of his daughter, who since suffered complications, but he trained with the squad on Monday and Moore must decide whether to hand him an instant recall or keep faith with Jamie Annerson.
Moore has no fresh injury concerns to contend with and has been boosted by the return to training of Dale Tonge, who has recovered from a metatarsal injury suffered in pre-season.
Northampton will be without Liam Davis. The left-back was sent-off in the ninth minute of Saturday`s 4-1 thrashing at lowly Barnet - the Cobblers' fifth red card in the last nine games - and serves a one-match ban.
Veteran Marcus Hall will come back into the side as a ready-made replacement while manager Ian Sampson will have striker Leon McKenzie available.
McKenzie scored at Underhill but was replaced at the break as Sampson saved his legs for the trip to the Don Valley Stadium.
Sampson may be forced to make changes in midfield after playing for 80 minutes with 10 men so Kevin Thornton, Paul Rodgers and Michael Jacobs could all come in.
Striker Tadhg Purcell is out for the rest of the season with serious knee ligament damage.
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