Tottenham: Gomes, Hutton, Dawson, Bassong, Assou-Ekotto, Lennon, Palacios, Modric, Bale, Pavlyuchenko, Defoe. Subs: Cudicini, Bentley, Keane, Crouch, Giovani, Corluka, Sandro.
Chelsea: Cech, Ferreira, Ivanovic, Terry, Cole, Ramires, Mikel, Essien, Kalou, Anelka, Malouda. Subs: Turnbull, Lampard, Drogba, Sturridge, Van Aanholt, Bruma, McEachran.
Luka Modric has warned his Tottenham team-mates overconfidence could prove fatal against the misfiring Blues.
In-form Spurs have been tipped to pile on the misery for Carlo Ancelotti's champions, who have won just two of their last eight games in all competitions.
That has seen them surrender top spot in the league, while defeat would move fifth-placed Tottenham to within a point of their city rivals.
But Modric insists expecting anything other than a Blues backlash could scupper Spurs' chances of completing a hat-trick of home wins against them.
"Okay, sure, they have some problems at the moment but that means nothing," the midfielder said in the club's official matchday programme.
"If we think we will beat them or we are favourites then it's the wrong attitude.
"We need to give them massive respect but, at the same time, we believe in our strength and quality and we are all determined to beat them at home for the third time in row.
"We know they are a dangerous side full of great players, unbelievable players.
"When we get out on the pitch we need to play our game, to fight for every ball, to play with confidence and try to beat them again.
"We are in good form and we fear no-one at home."
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