Plymouth can include Bradley Wright-Phillips in their squad to face Oldham after his move to Reading fell through.
The striker will be in contention after being rested for games against Bournemouth and Huddersfield as he discussed a move to the Madejski Stadium.
The former Manchester City man leads the npower League One scoring charts with 13 goals and could be partnered by Joe Mason, who hit a brace against the Terriers.
Defenders Curtis Nelson and Stephane Zubar were both shown the red cards at the Galpharm Stadium. The former has appealed the decision, but the latter will definitely sit out the clash.
Manager Peter Reid was also ordered from the Argyle dug-out for comments he made about the referee and will face a wait to see if he is to be charged with misconduct by the FA.
Oldham duo Dean Kelly and Jason Jarrett have been released from Boundary Park with immediate effect ahead of the trip.
The pair were on short-term contracts which were due to expire later this month so will play no part at Home Park.
Manager Paul Dickov said: "They are both great professionals and I would like to wish them well in their future careers.
"Dean expressed a wish to go back to Ireland to be with his family. He has been here on his own and found it hard. Jason started well but, for whatever reason, things have not worked out as we had hoped."
Dickov has no new injuries after the midweek 6-0 home defeat against Southampton.
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: http://gms.to/writeforgms