Bradley Wright-Phillips made it two goals in two games to move Charlton up to fifth in the League One table.
The former Plymouth frontman was on hand to slot home from a Johnnie Jackson corner to give Chris Powell's side all three points.
Jackson was denied by Stephen Henderson early on before Paul Huntington headed over from a corner for Yeovil.
Terry Skiverton`s team dominated thereafter but could not make it count and were duly punished just after the hour mark.
Jackson swung over a corner and his delivery was pounced on by Wright-Phillips, who fired into the top corner from six yards.M
Defeat leaves the Glovers just two points above the relegation zone.
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