Carlisle defender Lubo Michalik and midfielder Liam Noble could return to the squad for the home clash with Plymouth.
On-loan Hull defender Liam Cooper will miss out through suspension, though, after his dismissal at Peterborough at the weekend.
Michalik has missed the last six games due to a torn hamstring, but manager Greg Abbott could turn to the Slovakia international following Saturday's 6-0 thrashing and the latest injury sustained by fellow centre-half Danny Livesey (hamstring).
Noble, on loan from Sunderland, will return to contention after a one-match ban, while Abbott could hand a late fitness test to winger Ben Marshall, who was forced off on Saturday following a late challenge by Posh defender Mark Little.
Skipper Paul Thirlwell returned to the substitutes' bench at Peterborough and could feature following his recovery from a calf injury.
Plymouth boss Peter Reid will be without Onismor Bhasera for the trip.
Left-back suffered knee ligament damage in the 34th minute of Saturday's 2-0 defeat at Hartlepool and had to be stretchered off.
The 25-year-old will undergo a scan over the next few days to determine the full extent of the injury.
Midfielder Simon Walton, who is yet to make a first-team appearance this season, will also miss out as he continues his rehabilitation from cruciate knee ligament damage by turning out for the reserves instead.
Fellow midfielder Chris Clark is available to return following his three-match ban.
Utility player Kari Arnason has overcome the hamstring problem which kept him out of the defeat at Pools and will return to the squad.
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