Manchester United will face Chelsea in the quarterfinals of the Champions league in a repeat of the 2008 final in Moscow.
The other English club still in the competition, Tottenham Hotspur, will face nine-time winners Real Madrid, with the victors set for a semi-final tie against either Barcelona or Shakhtar Donetsk.
Reigning champions Inter Milan face German side Schalke 04 in the other tie, the winner of which will face either United or Chelsea in the other semi-final.
The draw means the prospect of an all-English final, at Wembley in May, is still on the cards.
The draw in full:
Inter Milan v Schalke 04 / Chelsea v Manchester United
Real Madrid v Tottenham Hotspur / Barcelona v Shakhtar Donetsk