Macclesfield boss Gary Simpson will be without captain Paul Morgan when Stevenage visit Moss Rose.
The defender fell awkwardly on his right arm during Tuesday`s victory at Morecambe and is set to miss the rest of the season.
Physio Nick Reid said: "Unfortunately he has suffered a break and will need an operation on the arm, and a new plate putting in.
"He'll almost certainly be out for the rest of the season now which is a real blow."
Sam Wedgbury (hip) and Paul Bolland (hamstring) picked up injuries during last week`s 3-3 draw at home to Torquay and missed the midweek win at Morecambe.
The pair will remain sidelined but Carl Tremarco, Vinny Mukendi, Lewis Chalmers, Simon Yeo and Shaun Brisley are all fit after recent injuries.
Stevenage boss Graham Westley will wait on the fitness of defender Scott Laird before naming his squad.
The 22-year-old left-back suffered an Achilles injury 20 minutes into the second half of Tuesday night's 2-0 win at Burton and had to be replaced by midfielder Robert Sinclair.
However, the Boro boss is hopeful Laird will be fit enough to retain his place in the starting line-up.
Westley has no other injury or suspension problems and is unlikely to make too many changes to his line-up following a run of four consecutive league wins - the first time the club has ever achieved such a feat.
Midfielder Darren Murphy is pushing for his second start since returning from a broken leg after stepping off the bench in midweek to win the penalty for John Mousinho's second goal.
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