Plymouth manager Peter Reid will be without Rory Patterson for the clash with MK Dons.
Patterson lashed in Argyle's match-winner against Dagenham on Good Friday, but he was later sent off after picking up a second yellow card.
That means the striker is suspended and leaves boss Reid with a vacancy in attack.
He could retain defender Kari Arnason in the unfamiliar role, however he will be hopeful Rory Fallon can shake off a groin problem.
The New Zealander was pencilled in to start against the Daggers but was forced to withdraw prior to kick-off.
Simon Walton is also a doubt after he was forced off during the second period of Friday's win and Reid will give the midfielder as long as possible to recover before making a decision.
MK Dons will be without Rowan Vine for the trip.
Striker Vine's 93-day emergency loan from QPR expired after Friday's 3-1 home defeat to Huddersfield and he has gone back to Loftus Road after scoring once in 17 appearances for the Dons.
Defender Danny Woodards remains absent with a hamstring strain so Mathias Doumbe, who scored the consolation goal against the Terriers, will continue at right-back.
Manager Karl Robinson lamented his team's inability to take chances on Friday so it remains to be seen if he makes changes up front. However, top scorer Sam Baldock should retain his place after being recalled to the starting line-up versus Town.
On-loan QPR forward Angelo Balanta made his first start against Huddersfield since his recovery from an ankle problem that had kept him out for five months and it remains to be seen if he is fit enough to play two games in four days.
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