Exeter boss Paul Tisdale faces a striking crisis with several of his forwards set to miss the visit of MK Dons.
The Grecians were already without Daniel Nardiello, who is sidelined after being stretchered off before half-time in the Grecians` first league game, while John O'Flynn is recuperating from a knee operation.
Richard Logan hobbled off in the Carling Cup victory over Yeovil to compound Tisdale's injury woes.
Logan was replaced by Guillem Bauza, who grabbed a goal on his debut before he was also replaced as a precaution.
Loan signing Nicholas Bignall is likely to lead the line after making his Exeter bow against Yeovil.
"We have the benefit of Nicholas Bignall for a month, so let's be grateful and take advantage of that and then we will assess it a month's time," Tisdale told Western Morning News.
MK Dons have no new problems ahead of the trip.
Mathias Kouo-Doumbe remains the only absentee after the defender suffered ankle ligament damage during pre-season.
Adam Chicksen is expected to continue filling in at right-back and keep Tom Flanagan out of the defence.
Luke Chadwick was rested against Cheltenham in the Carling Cup in midweek and will hope to force his way back into the side.
However, Jabo Ibehre could keep his place in the starting XI after scoring his second goal in as many games at Whaddon Road on Tuesday night.
Goalkeeper Ian McLoughlin is back from international duty with the Republic of Ireland Under-21s and could replace Louis Bragg on the bench as David Martin's deputy.
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