Hope Akpan is back in the Crawley squad for the first Football League fixture at the Broadfield Stadium against Macclesfield.
Midfielder Akpan, a summer signing from Everton, missed Saturday's 2-2 draw against Port Vale through suspension having been sent off against AFC Wimbledon in their Carling Cup preliminary round play-off.
But defender John Dempster now has to sit out after he was dismissed for two bookings at Vale Park.
Dempster would have served his ban at Crystal Palace on Tuesday night but that match was postponed due to the riots in London.
First-choice goalkeeper Michel Kuipers' rib injury will be checked over while skipper Pablo Mills (ankle) and fellow defender Jamie Day (back) are still on the sidelines.
Macclesfield boss Gary Simpson could be boosted by the return of captain Paul Morgan for the trip to Crawley.
The defender missed the end of last season with a broken arm but is edging closer towards full fitness and may come into contention to face Steve Evans' side.
Tom Fisher (knee) and Vinny Mukendi (hamstring) remain sidelined and Waide Fairhurst will be assessed.
The striker was forced off after just 42 minutes of Saturday's 1-0 home defeat at the hands of Dagenham following a heavy challenge.
He played no part in Tuesday's shock 2-0 win at Hull in the first round of the Carling Cup - a result which left Simpson beaming with pride.
"They worked their socks off for each other," he said.
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