Bournemouth will begin life without Danny Ings against Stevenage.
The Cherries accepted a bid from Burnley and the teenage striker joined the Clarets on Monday.
Ings follows former Bournemouth boss Eddie Howe to Lancashire.
Manager Lee Bradbury will also be without midfielder Michael Symes as he is still struggling with a back injury but much-travelled striker Steve Lovell could make a return from his injury.
Joe Partington will be sidelined until September with his hip problem.
Youngsters Alex Parsons and Dan Strugnell won't be involved for the Cherries for three months after the club announced that they will both go on loan to Southern League club Wimborne Town.
Stevenage will be without the suspended Michael Bostwick.
Bostwick received two yellow cards and was subsequently sent off midway through the second half of the 1-1 draw at fellow League One newcomers Chesterfield on Saturday. He will serve a one-match ban.
Summer signings Jennison Myrie-Williams and Robin Shroot could come into contention to replace the midfielder.
Ahead of the trip to the south coast, Boro boss Graham Westley told the club's official website: "They are a play-off team in this division and beating Sheffield Wednesday 2-0 at the weekend shows where they are at.
"But we like the big occasion and the big games, we will rise to it and we are looking forward to it."
Copyright (c) PA Sport 2009, All Rights Reserved.
Do YOU want to write for GiveMeSport? Get started today by signing-up and submitting an article HERE: http://gms.to/writeforgms