Spain v Chile
September 2, kick-off: 19:45
Stade de Genève
Spain boss Vicente Del Bosque will be without Barcelona duo Gerard Pique and Carles Puyol as the world champions take on Chile in Geneva.
Also missing is Andoni Iraiola, while Del Bosque has called up uncapped trio Alvaro Dominguez, Sporting Gijon defender Alberto Botia and Barcelona B player Martin Montoya to fill in.
Baca-Real rivalry no problem for Del Bosque
Despite the supreme footballing talents of Barcelona and Real Madrid, the two sides seem to create headlines for the wrong reasons when the encounter each other.
The last time the Spanish giants met, a touchline melee saw a red-card frenzy and Jose Mourinho indulging in some particularly unsporting behaviour.
Naturally, the more petty this rivalry becomes, the more questions will be raised about the ability of the Spanish players to put aside their differences when they gather for international duty.
But Spain coach Vicente Del Bosque can't foresee any problems with team spirit in the camp of the world champions.
"I'm left with the positive of that match, of the image left by the quality of our football," Del Bosque said. "The last time we gathered everything was positive and I don't expect things to change now."
Meanwhile, Del Bosque will use Friday's friendly against Chile in Geneva to blood some youngsters into the senior set-up.
The 60-year-old took the decision to leave experienced duo Carlos Marchena and Joan Capedevila out of the squad but says that competition for places can only be positive going forward.
"There are some new names in the list but that doesn't mean we're eliminating others like (Carlos) Marchena and (Joan) Capdevila from future squads," Del Bosque added.
"We're using this opportunity to bring in young players so we get to know them better. We're well covered."