Manchester City v Everton
Manchester City kick off this weekend's Barclays Premier League action, welcoming Everton to the Etihad Stadium.
David Moyes' side are facing a tough challenge, with City unbeaten in all competitions and yet to concede a goal at home this season.
Owen Hargreaves and Kolo Toure are in contention to start after impressing in the Carling Cup in midweek.
Arsenal v Bolton
Arsenal take on Bolton at the Emirates Stadium, with both sides aiming to reverse their fortunes after poor starts to the season.
Arsene Wenger has a full strength squad, with Robin van Persie, Theo Walcott, Aaron Ramsey and Gervinho set to form an imposing attacking force.
Stoke v Manchester United
League leaders Manchester United travel to Stoke looking to maintain their 100% record after a blistering start to their campaign.
Rio Ferdinand could return to the side to marshal the defence alongside Phil Jones, but Javier Hernandez is a doubt after picking up a knee injury.
Liverpool v Wolves
Liverpool face Wolverhampton at Anfield with Steven Gerrard set to make his Anfield return after featuring in the Carling Cup this week.
The Liverpool captain is almost certain to play some part, while Andy Carroll faces competition from Craig Bellamy for a starting place.
Chelsea v Swansea
Andre Villas-Boas will demand his side bounce back from last week's dissapointing defeat at the hands of Manchester United when Chelsea face Swansea.
Fernando Torres is expected to start as he looks to overcome his infamous miss at Old Trafford. The Spaniard is likely to be flanked by Juan Mata and Nicolas Anelka out wide.
Wigan v Tottenham
Two impressive league wins and the signings of Emmanuel Adebayor and Scott Parker have lifted spirits at White Hart Lane after a disheartening start to the season.
Spurs will be firm favourites going in to their fixture at Wigan, with Jermain Defoe set to continue his partnership with Adebayor up front after the duo scored 5 goals between them in the last two games.
Newcastle v Blackburn/West Brom v Fulham
Elsewhere in the Premier League, Blackburn visit Newcastle at St James Park with a newfound confidence, while Fulham visit West Brom looking for their first win.
On Sunday QPR and Aston Villa bring another weekend of top flight football to a close, with Neil Warnock's side looking increasingly impressive since spending heavily in the transfer window.