Sunderland defender Titus Bramble has been arrested on suspicion of sexual assault and possession of a class A drug.
The 30-year-old was being held for questioning by Cleveland Police following an incident in the early hours.
A force spokeswoman said: "A 30-year-old man from Wynyard has been arrested on suspicion of sexual assault and possession of a class A drug. He is currently being questioned by police and inquiries are ongoing."
Last year Bramble, who played in his team's 2-1 defeat at Norwich on Monday, was arrested by Northumbria Police over an alleged rape in a Newcastle hotel but he was later released without charge.
His brother Tesfaye was jailed for four and a half years last month after he was convicted of raping a 19-year-old a year ago.
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