Scunthorpe boss Alan Knill looks set to restore Sam Togwell, Damien Mozika and Chris Dagnall to his starting line-up for the game with Leyton Orient.
Knill chose to rest the trio on Tuesday when the Iron were knocked out of the Johnstone's Paint Trophy after a 1-0 defeat to Oldham.
Centre-back Niall Canavan is back in training and could be available after recovering from an ankle injury which has kept him sidelined for five weeks.
On-loan midfielder Oliver Norwood is unavailable as he has been called up to the Northern Ireland senior squad.
Defender Paul Reid has been told by a specialist that he will miss four weeks with a broken nose, but Scunthorpe's physio thinks he will be available sooner.
Right-back Cliff Byrne (back) has returned to training but is unlikely to feature while Jimmy Ryan (knee), Michael Collins (tendonitis), Jordan Robertson (broken foot), Josh Lillis (knee) are all out.
Jamie Cureton is pushing to start for Leyton Orient.
The striker returned from a month on the sidelines with a groin injury as a substitute against Preston last weekend, and then scored for the reserves at Tottenham in midweek.
But boss Russell Slade may opt to stick with the starting line-up which secured Orient's first win of the season at the 11th attempt.
Full-back Charlie Daniels and midfielder Jimmy Smith missed out against Preston with thigh problems and remain doubtful.
Lee Butcher continues in goal as Ben Alnwick (groin), Jamie Jones and David Button (both shoulder) are still sidelined, while striker Jonathan Tehoue is not expected back until December due to a broken wrist.
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