Liverpool and Manchester United kick off this weekend's Barclays Premier League action in a huge clash at Anfield on Saturday.
Ahead of the game, Kenny Dalglish sought to down play the bitter rivalry between the two most successful teams in English football.
Steven Gerrard is likely to return to the starting line up, with Liverpool keen to extend their three consecutive wins over United at Anfield.
Wayne Rooney meanwhile will be looking to put a difficult week behind him by firing the Red Devils to victory alongside Danny Welbeck.
Second place Manchester City face Aston Villa at the Etihad Stadium, with both sides still unbeaten - and City yet to concede a goal at home.
Roberto Mancini hinted he would not risk Sergio Aguero, and with Carlos Tevez certain to be left out, Mario Balotelli is in line to head the attack.
Only three points will be enough for Chelsea when they welcome Everton to Stamford Bridge as they look to keep pace with the league leaders.
With Fernando Torres suspended, Didier Drogba, Juan Mata and Daniel Sturridge are set to form an imposing attacking line up for the Blues.
Elsewhere on Saturday, Stoke face Fulham, with Peter Crouch looking to lead the Potters to their first league win for over a month.
Bolton meanwhile travel to Wigan determined to kick start their season after a frustrating run of results that has left them bottom of the table.
Also in Premier League action are newly promoted sides Norwich and Swansea, while QPR welcome struggling Blackburn to Loftus Road.
On Sunday, Arsene Wenger will be demanding his misfiring side secure a win against Sunderland after an indifferent start to their season.
Lauren Koscielny returns to strengthen a leaky Arsenal defence, while on loan Gunner Nicklas Bendtner is ineligable to face his parent club.
Tottenham face a tricky journey to St James' Park, with Harry Redknapp aiming to overcome a Newcastle United side who are so far unbeaten.
But Emmanuel Adebayor is a doubt for the away side as they attempt to extend their impressive four game winning streak on Sunday.
Finally on Sunday, West Brom and Wolves bring the weekend's football to a close, with both hoping to get back to winning ways.