Sir Alex Ferguson has injury concerns over five players ahead of Manchester United's weekend encounter with Sunderland in the Barclays Premier League on Saturday.
Brazilian midfielder Anderson, and Michael Owen are the latest players to pick up knocks, and join the likes of Chris Smalling, Ashley Young, and Tom Cleverley on the treatment table at Old Trafford, ruling them out of facing the Black Cats.
On a more positive note, Red Devils captain Nemanja Vidic is available for selection after his midweek suspension in the 2-0 win over Otelul Galati in the UEFA Champions League on Wednesday.
"Vidic will be back but maybe Anderson is the one player who picked up an injury," Ferguson confirmed. "We'll see what he's like.
"He could be doubtful. There will be no returns for Young, Smalling or Cleverley though."
Meanwhile, Owen was injured in the build-up to Antonio Valencia's opener, and Ferguson has sympathy for the striker who has waited patiently for his first-team chance.
"Michael injured his thigh when he made the run across the front post for the first goal," he continued. "It's a killer for him. He started the season well, he's been training terrifically.
"His two performances in the League Cup have been great. He made the goal last night, no doubt about that. I hope he's not out for too long. We've assessed him this morning, he's had a scan but we don't have any results from that yet."