Sir Alex Ferguson says he will perform a complete overhaul of his matchday squad for this week's Carling Cup quarter-final with Crystal Palace.
United host the Eagles at Old Trafford on Wednesday night in the first leg of their tie, and the home side will rest a number of key individuals.
This is a pattern Ferguson has followed for the entire cup campaign, and will once again use the game with Palace to provide his youngsters with a chance to impress.
The likes of Ravel Morrison and Ezekiel Fryers will get an opportunity to prove their worth, while Mame Biram Diouf and Federico Macheda are in desperate need of game time.
Chris Smalling could also feature after returning to action against Benfica and Newcastle, although Ferguson is unsure over the make-up of his midfield for the visit of Palace.
"There will be complete change," he told manutd.com. "Just the same as we had at Leeds and Aldershot.
"Ravel Morrison was in the squad for Wednesday's game [against Benfica]. He's a very, very talented boy, of course, and he'll possibly be on the bench, at least, in midweek.
"But I've got other players needing a game like Mame Biram Diouf and Federico Macheda.
"All the younger players [will come in] - Zeki Fryers, the two Da Silvas [Rafael and Fabio] are possibles.
"The only area where I've got problems is centre midfield. It's possible I could play [Paul] Pogba in there but we'll wait and see. I've got enough players to choose from, that's for sure."