Chelsea v Liverpool; Stamford Bridge; Carling Cup; Tuesday 29 November 2011, 19:45
Chelsea will be without the services of club captain John Terry who serves a one match suspension following his booking in Saturday's 3-0 Barclays Premier League victory over Wolves.
Andre Villas-Boas could recall Fernando Torres to the starting line-up to face his former club, while Romelu Lukaku, Oriol Romeu and Josh McEachran are also set to start.
However, another former Red Raul Meireles is cup-tied and so will not feature.
For Liverpool, Kenny Dalglish will welcome back Craig Bellamy, after the Welshman was omitted from Sunday's match-day squad that drew with Manchester City following the death of international manager and mentor Gary Speed.
Vice-captain Jamie Carragher is expected to come into the side and Andy Carroll is also in line to start.
Turnbull targets Liverpool victory
Chelsea goalkeeper Ross Turnbull has enjoyed an eventful Carling Cup campaign, having featured in both wins against Fulham and Everton to set up tonight's quarter-final clash with Liverpool.
The 26-year-old stopper came on as a second-half substitute against the Cottagers, and played his part in ensuring the Blues' progression, pulling off a string of superb saves, which resulted in the game going to a penalty shoot-out.
"We have been lucky in the two games that our opponents have missed two penalties in normal play," said Turnbull. "But you gain your own luck by the attitude the lads have put into the tournament."
In the next fixture against Everton at Goodison Park, Turnbull was selected from the start, but received his marching orders on the hour mark when he brought down Louis Saha in the box to concede a penalty of his own.
Petr Cech excelled as the replacement keeper, saving the resulting spot-kick, and although the Toffees did later equalise, Daniel Sturridge regained the advantage to put Chelsea in the last eight, where they face a Barclays Premier League opponent for the third consecutive time.
"The draw has not been kind to us but that is part and parcel of it if we are going to go on and win the competition," Turnbull added.
"It is going to be a tough game but you have to beat teams like Liverpool when the aim is to pick up a trophy."