Harry Redknapp was forced to defend his team selection after Tottenham were beaten by PAOK Salonika in the Europa League on Wednesday night.
The Greek side triumphed 2-1 at White Hart Lane despite being down to 10 men for over half the game.
Redknapp made nine changes to the side that had beaten West Brom at the Hawthorns on Saturday, with only Jermain Defoe and Aaron Lennon retaining their places.
Spurs now face an uphill task of progressing out of their group and into the last 32 of the competition, and Redknapp says he altered his side for the benefit of the league campaign.
"It was a different team and it is hard when you make a lot of changes," Redknapp said.
"We have been lucky so far and the important thing is that we have the players fresh for the Premier League at the weekend.
"We have changed the team in this competition and that is why we have done so well in the league, where we have won nine and drawn one in our last 10 games.
"If we had Roman Pavlyuchenko and Giovani Dos Santos fit, we would not have played Luka Modric, Jermain Defoe or Aaron Lennon."
He added: "I am disappointed now because we are not going to be in the last 32.
"It's very slim - it is very difficult now."