Wigan Athletic v Liverpool; DW Stadium; Barclays Premier League; Wednesday 21 December 2011, 19:45
Wigan boss Roberto Martinez has a fitness concern over Colombian striker Hugo Rodallega, who picked up an injury in the weekend draw against Chelsea.
Meanwhile, Emmerson Boyce is back in training following his recent hamstring injury but tonight's clash with Liverpool will come too soon for him.
Liverpool are still without midfielder Jay Spearing, who serves the final game of his three-match ban this evening, and Kenny Dalglish may choose to rest Welshman Craig Bellamy, after his recent run of games.
Reds captain Steven Gerrard remains sidelined with an ankle injury, and is still a number of weeks away from a first-team return.
Skrtel sets sights on Wigan
Liverpool defender Martin Skrtel is hoping to extend the club's excellent away form by ending their so-called 'hoodoo' when they visit Wigan Athletic this evening.
The Reds have failed to win at the DW Stadium in their last three attempts - drawing twice and losing the other tie, with the last victory coming in 2007.
Skrtel is hoping to end the calendar year on a high, and with nine points still to play for, the Slovakian international stopper is expecting a strong performance from his teammates.
"The Christmas period is very important for every single team and our aim is to get back maximum points from every game we play," said Skrtel.
"You know you are always in for a difficult game when you play away against a team like Wigan, Stoke or Bolton, because they have a similar style of playing.
"We will have to fight hard to get the victory and they got a good point on Saturday when they drew with Chelsea.
"I think we are due some good fortune away at Wigan. We have to break this barrier of not winning there for three years and hopefully this could be a good time to do it."
When asked about why the players seem to have struggled to carry their good away form back to Anfield, Skrtel added:
"I don't know why results have been better away from home but our aim always is to try and win every game.
"I think we have played really well overall at Anfield but sometimes haven't got the results our performances have deserved.
"We are still creating a lot of chances and we hope to score more goals in the future."