Manchester United v Bolton Wanderers
Barclays Premier League
Saturday, January 14th; 15:00
Rio Ferdinand is set to recover from a mid-week stomach illness to start for Manchester United in the absence of Chris Smalling and Phil Jones, who picked up injuries during last season's derby victory.
Gary Cahill is likely to make his final appearance for Bolton at Old Trafford after his move to Chelsea failed to be completed on Friday.
The England defender will partner either Zat Knight or David Wheater at the heart of the Trotters back-four, while Jussi Jaskelaainen is set for a return in goal.
Ferguson laments defensive injury blow
Manchester United Sir Alex Ferguson is likely to be without defensive pair Chris Smalling and Phil Jones after they both picked up injuries during last weekend's derby win over Manchester City.
Jones has been a near ever-present for United in the league this season, while Smalling was making his first appearances for over two weeks after missing the defeats to Blackburn Rovers and Newcastle United.
Without the duo, Ferguson will be forced to field Rio Ferdinand, who has been fighting a virus this week, and Jonny Evans, who has been in and out of the United team this season with fitness and form eluding him for most of the campaign.
"We've got one or two doubts for tomorrow," Ferguson said.
"Smalling and Jones picked up knocks in the derby. We'll see what they're like tomorrow. Anderson got a knock in training, but hopefully he'll be okay.
"So we've got a reasonable squad for tomorrow. And we need a good performance against a team that will battle for everything. Any team near the bottom of the table will do that, as we experienced at home to Blackburn. We went into the Blackburn game with respect for them but it wasn't a great performance.
"We have to address Bolton's challenge properly. It's a local derby too, which adds something to it."
Coupled with their plight in the relegation zone in the Premier League, Owen Coyle's Bolton face a tough task upon their visit to the champions having won just one of the last 18 meetings between the sides.
A change in fortunes has seen Wanderers lose just one of their last five, with their last league outing producing a spirited win over Everton.
Manager Coyle has called on his players to be brave when traveling to the Theatre of Dreams.
"Any player, coach or manager wants to compete against Manchester United," he said
"They are one of the elite clubs in world football and if you have a passion for the game then you want to play against the very best.
"For our part, we are under no illusions of how difficult our task will be, but having said that, we are in a decent run of form and the players are playing well," Coyle added.
"We are passing and moving the ball, so we go there with a belief that we can be really positive, be brave in possession and get points from the game.
"All I want is for the players to go out there, give their very best and more often than not when you do that you will get results to go with it."