The 25-year-old Bosnian international ended his 11 game barren spell when he rose to net the winner in Monday evening's 1-0 Barclays Premier League victory over Wigan Athletic at the DW Stadium.
Despite his goalless run, Dzeko has netted an impressive 14 goals in 2011-12, but only two of which have come from headers - a modest return for a powerful forward who boasts a 6ft 4in frame.
"I hope this is the start of a new Dzeko," reflected Mancini. "This guy deserves to be important. He deserves to score - that is important for the strikers.
"I certainly think we can exploit his size more. He can score with his head because he is strong in the air."
Next up for City is a home clash with title-rivals Tottenham Hotspur at the Etihad Stadium on Sunday, and Mancini will be hoping that Dzeko can build on his goalscoring return in a bid to help fire the Barclays Premier League leaders to glory.
The £27million hitman was on target four times when the Citizens romped to a 5-1 victory at Whit Hart Lane back in August, and whilst this weekend's meeting is expected to be less one-sided affair, Dzeko will be hoping for another match-winning contribution.