The 18-year-old starlet has grown frustrated at a lack of first-team opportunities for the Red Devils, having been limited primarily to appearances in the Carling Cup this season.
Sir Alex Ferguson is keen to keep Pogba at Old Trafford as he sees him as a great prospect for the future, but after officials from the Serie A outfit arrived in Manchester last week to register their interest, the youngster appears to have had his head turned.
The French U19 international joined Manchester United from Le Harve in 2009, and has been targeted for a first-team breakthrough next season.
However, Ferguson's plans now look to have been dashed as Juventus aim to complete a cut-price deal for Pogba, who has also attracted interest from both Milan clubs.
Pogba is one of a number of young Manchester United players approaching the end of their respective contracts, with Ravel Morrison the other high-profle academy graduate who looks to be leaving for pastures new, with West Ham poised to complete a £650,000 deal to take him to Upton Park.