Arsenal v Chelsea
Arsenal and Chelsea kick off this weekend's Premier League action, with both sides chasing a top four finish and Champions League qualification.
Chelsea are just two points behind fourth placed Tottenham, with confidence high at Stamford Bridge since Roberto Di Matteo took charge of the team.
Fernando Torres is expected to start up front with Didier Drogba to be rested ahead of next week's crucial Champions League semi-final 2nd leg at Barca.
Arsenal are without Mikel Arteta, who has been ruled out for with an ankle injury, while Yossi Benayoun is ineligible to face his parent club.
QPR v Tottenham
Tottenham are away at Loftus Road, desperate to get their top four challenge back on track, with only one win in their last six league matches.
Newcastle v Stoke
Harry Redknapp's side need a win to hold off high flying Newcastle United. Alan Pardew's men have won five straight games to move into fifth place.
Fulham v Wigan
Wigan will be looking to build on impressive wins against Arsenal and Man Utd when Roberto Martinez's side travel to Craven Cottage.
Aston Villa v Sunderland; Bolton v Swansea; Blackburn v Norwich
Elsewhere, Villa welcome Sunderland, Bolton face Swansea at the Reebok, while struggling Blackburn Rovers could do with a win over Norwich.