Jordan Henderson has been put on red alert after Frank Lampard suffered a thigh injury on Wednesday afternoon, leaving his Euro 2012 involvement hanging in the balance.
Henderson, who has endured a difficult campaign with Liverpool, could be set for an unlikely call-up to the national side in the wake of this latest injury setback for Roy Hodgson's men.
England are already without Manchester City midfielder Gareth Barry, who was ruled out of this summer's competition following a stomach injury sustained in last weekend's 1-0 friendly victory over Norway in Oslo.
And with Lampard's injury scare providing more cause for concern, England's lack of strength in depth is beginning to be exposed.
If Henderson is on the receiving end of a last-minute call-up, the Three Lions will be short of experienced alternatives in central midfield, with the likes of Michael Carrick being overlooked from Hodgson's initial squad altogether.
Lampard, the 33-year-old Chelsea midfielder, only joined up with his England colleagues on Tuesday after playing a key role in Chelsea's action-packed Champions League final win over Bayern Munich on 19th May.
Along with his Chelsea counterparts John Terry, Ashley Cole and Gary Cahill, Lampard, who has represented his country on no fewer than 90 occasions, was given extra time off to recover after the drama of their penalty shoot-out victory.
If Lampard is forced to withdraw, it will be a major blow to England's Euro hopes given that he finished the season in such fine form.
But with the FA confirming that Henderson has been placed on stand-by, the Liverpool midfielder will see this as an opportunity to prove his doubters wrong at both international and club level if called upon.