Santos are looking to replace Ganso with fellow Brazil international Kaka, according to coach Muricy Ramalho.
Kaka is thought to be surplus to requirements at the Bernabeu, and Jose Mourinho has hinted he's willing to let the Brazilian leave Madrid in search of first-team football.
And Santos have now taken pole position in the race for Kaka. The sale of Ganso to rivals Sao Paulo has opened up a place in the Santos team, and ESPN reports Kaka is the prime target.
"Who would have thought that Sao Paulo could pay that kind of money for Ganso? Anything is possible," said Ramalho.
"Kaka is an option, and so are Diego and Robinho," continued the Santos coach.
Diego and Robinho are both former-Santos players and have been repeatedly linked with a return to their old club. Kaka was rumoured with a second spell at AC Milan, but after that failed to materialise, his wife revealed the Brazilian star would only consider a move back to his native country.
The three targets are huge names not just in Brazil, but Europe as well, and were, at one stage, among the biggest names in world football.
30-year-old Kaka is one of the world's most expensive players - his move from Milan to Madrid cost the La Liga club £56m - and the Brazilian won the 2007 Ballon d'Or, and a Champions League the same year.
Robinho was once the British record transfer holder, having moved from Real Madrid to Manchester City for £32.5m on deadline day.
And Diego, who played alongside Robinho at Santos, was talked about as a future world-class player in the early-to-mid 2000s. His career stalled somewhat after leaving Santos - spells at Porto, Werder Bremen, Juventus and Wolfsburg were all mildly successful - but he hasn't enjoyed the same high profile as the other two.
Still, Diego has won 33 international caps. All three at the same club would be a huge coup for Santos, especially as they have managed to hold onto key asset Neymar.