Arsenal will look to claim their first win in three games when they go up against Fulham at Emirates Stadium on Saturday.
Saturday’s late kick off sees Manchester United travel to Villa Park to take on Aston Villa, with Sir Alex Ferguson’s side aiming to continue their recent run of good form.
In Saturday’s other big games, bottom club Southampton will look for their second win of the season against Swansea, Everton will look to continue their fine start to the season against Sunderland, and Stoke place host to win-less QPR.
Sunday brings with it a host of big Premier League fixtures, starting with Tottenham’s trip to take on Manchester City at the Etihad Stadium.
Mario Balotelli broke Tottenham hearts the last time the two side’s met, and the north London club will be hoping for revenge as well as three points to boost their top four charge.
Chelsea’s league form has dropped off somewhat since their lightning start, and they will have a tough task in recapturing top spot when they go up against Liverpool at Stamford Bridge.
Sunday’s final game sees West Ham go head to head with Newcastle at Saint Jame’s Park