Coach Avram Grant lost the Portuguese defender with a back injury in the first half of their 1-1 draw with Everton, and joins captain John Terry, goalkeeper Petr Cech and full-back Paulo Ferreira in the treatment room.
And Grant confessed: "We have too many injuries. It is not easy to play without all the back four and goalkeeper from the last few months. This is the reason we have a big squad, but it is unusual. Chelsea have the best two left-backs in England, and Ashley Cole is fit for England."
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