Manchester United scored a potentially decisive away goal as they drew 1-1 with Real Madrid in the first leg of their Champions League last 16 tie.
Danny Welbeck gave the Premier League leaders the advantage before Cristiano Ronaldo restored parity at the Santiago Bernabeu on Wednesday night.
Four other English clubs are in European competition on Thursday, as Chelsea, Liverpool, Newcastle and Tottenham enter into the last 32 of the Europa League.
Chelsea travel to Sparta Prague after having been knocked out of the Champions League, Spurs host French giants Lyon, while Liverpool and Newcastle are in action against Zenit St Petersburg and Metalist Kharkiv respectively.
Chelsea No.1 Petr Cech is set to face his former club despite a broken finger, and hopes to follow last season's Champions League success with another European triumph.
Tottenham, meanwhile, are set to start with Michael Dawson, and Spurs boss Andre Villas-Boas says he is thankful for not selling the defender last summer.
Arsenal legend Thierry Henry has told supporters of they club they need to stop moaning about Arsene Wenger.
Henry says Wenger still deserves the respect of fans for his previous achievements.
The possibly pivotal Manchester derby in April has been moved by the Premier League to a Monday night.
The fixture on April 8th will be the first time Manchester City have been to Old Trafford since they handed out a 6-1 drubbing in their title winning campaign.
Barcelona midfielder Alex Song hopes he can provide the Camp Nou club with the next Lionel Messi.
Song, who joined from Arsenal last summer, says his two young sons are desperate to emulate their Barcelona hero.